منابع مشابه
Human leptin: from an adipocyte hormone to an endocrine mediator.
Leptin is a mainly adipocyte-secreted protein that was discovered 5 years ago. Most of the research following this discovery focused on the role of leptin in body weight regulation, aiming to illuminate the pathophysiology of human obesity. However, more and more data are emerging that leptin is not only important in the regulation of food intake and energy balance, but that it also has a funct...
متن کامل“Role of the adipocyte hormone leptin in cardiovascular diseases – a study from Chennai based Population”
BACKGROUND Obesity is currently regarded as a pro-inflammatory condition during which leptin (Ob gene product) might act as a risk factor for Cardiovascular Diseases (CVD) including Acute Myocardial Infarction (AMI). There is a marked increase in circulating leptin concentrations and inflammatory markers such as Tumor Necrosis Factor-α (TNF-α) in AMI patients but still the association of leptin...
متن کاملAdipocyte iron regulates leptin and food intake.
Dietary iron supplementation is associated with increased appetite. Here, we investigated the effect of iron on the hormone leptin, which regulates food intake and energy homeostasis. Serum ferritin was negatively associated with serum leptin in a cohort of patients with metabolic syndrome. Moreover, the same inverse correlation was observed in mice fed a high-iron diet. Adipocyte-specific loss...
متن کاملThyroid Hormone and Leptin in the Testis
Leptin is primarily expressed in white adipose tissue; however, it is expressed in the hypothalamus and reproductive tissues as well. Leptin acts by activating the leptin receptors (Ob-Rs). Additionally, the regulation of several neuroendocrine and reproductive functions, including the inhibition of glucocorticoids and enhancement of thyroxine and sex hormone concentrations in human beings and ...
متن کاملAdipocyte-derived hormone levels in HIV lipodystrophy.
OBJECTIVE Despite evidence for the role of adipocyte-derived hormones in insulin resistance, little is known about their levels in human lipodystrophic states. We examined the relationships of plasma leptin and adiponectin levels to fat distribution and insulin sensitivity in the HIV lipodystrophy syndrome. DESIGN Cross-sectional study SETTING HIV primary care practices PATIENTS HIV-infec...
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ژورنال
عنوان ژورنال: Ceylon Medical Journal
سال: 2014
ISSN: 2386-1274,0009-0875
DOI: 10.4038/cmj.v46i4.6425